Bianca Andreescu defeated Donna Vekic 6–1, 3–6, 6–2 in the first round of the Rome Masters on clay on 9 May 2025, securing an upset victory against the pre-match favourite. Despite entering as the underdog at 2.2 odds to Vekic's 1.74, Andreescu controlled the opening set decisively before surrendering the second to her Croatian opponent. The Canadian regrouped decisively in the decider, reasserting her dominance to close out the match in straight sets. The result marks a notable scalp on the red clay and suggests Andreescu's form is sharpening ahead of the French Open.