Jannik Sinner defeated Eliot Spizzirri 4–6, 6–3, 6–4, 6–4 in the second round of the Australian Open on hard court. Sinner, the overwhelming pre-match favourite at odds of 1.01, recovered from dropping the opening set to dominate the remaining three frames and advance comfortably. Spizzirri, competing at 33.15 odds, mounted early resistance but could not sustain the level required to trouble the Italian second seed. Sinner's clinical conversion of opportunities after the first set underscored his superiority and progression through the draw.