Holger Rune defeated Roberto Bautista Agut 6–7, 6–4, 6–3, 6–2 in the first round of Roland Garros on clay on 26 May 2025, confirming his status as the pre-match favourite with odds of 1.18 to Bautista Agut's 5.67. After dropping a tight opening set to the Spaniard in a tiebreak, Rune seized control to claim three consecutive sets and advance comfortably. The Danish player's ability to recover from the first-set loss and consolidate his dominance across the following three sets demonstrated the composure required on the Roland Garros clay. Rune's progression to the second round maintains his momentum in the tournament.