Novak Djoković defeated Laslo Djere 6–4, 6–4, 2–0 at the US Open on hard court in the first round, confirming his status as overwhelming pre-match favourite with odds of 1.02 to Djere's 31.6. The Serbian top seed progressed with clinical efficiency, dropping just six games across two completed sets before the match was curtailed. Djoković's dominance in the early stages of the tournament underscores his intent to challenge for a fifth US Open title, whilst Djere's loss represents a difficult opening to his campaign on the season's final Grand Slam.