Novak Djoković defeated Learner Tien 6–1, 7–6, 6–2 in the first round of the US Open on hard court on 24 August 2025, confirming his status as the overwhelming pre-match favourite. The Serbian top seed controlled the opening set with ease, though Tien mounted a more competitive challenge in the second set, forcing a tie-break before Djoković prevailed. The third set saw the favourite reassert dominance to seal a straightforward progression. Djoković's comfortable victory underlines his continued fitness and form at the year's final Grand Slam as he advances deeper into the draw.