Lorenzo Musetti defeated Mariano Navone 4–6, 6–4, 6–3, 6–2 in the second round of Roland Garros on clay on 30 May 2025, confirming his status as the heavy pre-match favourite with odds of 1.12 to Navone's 7.59. After dropping the opening set, Musetti steadied himself to control the next three frames, progressively tightening his grip on the match as Navone's resistance crumbled. The Italian's ability to recover from the first-set deficit and dominate the closing stages demonstrated the composure and clay-court expertise expected of a seeded player at the French Open. Musetti's progression to the third round reinforces his credentials as a genuine contender on Roland Garros' surface.