Novak Djoković defeated Roman Safiullin 6–1, 6–2 at the Monte Carlo Masters on clay in the second round on 9 April 2024. As the heavy pre-match favourite with odds of 1.17, Djoković delivered an emphatic performance to justify his status, dismantling the Russian opponent in straight sets. The Serbian champion's dominant display on the Principality's red clay underscored his continued mastery of the surface and his readiness in the early stages of the tournament. Djoković's progression maintains his formidable record at Monte Carlo and sets up a meeting with a higher-ranked opponent in the subsequent round.