Nicolas Jarry defeated Holger Rune 4–6, 4–6, 7–5, 6–3, 6–4 in the first round of Wimbledon on grass on 30 June 2025, delivering a significant upset against the pre-match favourite. Rune, seeded higher with odds of 1.30, dominated the opening two sets, but Jarry mounted a sustained comeback to claim three consecutive sets and secure victory. The Chilean's resilience from two sets down demonstrated tactical adjustment on the grass surface, where Rune's early dominance proved insufficient to close out the match. This result represents a notable scalp for Jarry at the Championships and signals potential vulnerability in Rune's grass-court game despite his favoured status entering the contest.