Novak Djoković defeated Mackenzie McDonald 6–3, 6–3, 6–3 in the first round of Roland Garros on clay, as the heavy favourite with odds of 1.02. The Serbian top seed dismantled the American in a commanding performance, dropping just nine games across three sets and advancing without significant resistance. McDonald, operating at 22.07 odds, offered minimal threat to Djoković's clay-court mastery, allowing the world number one to progress smoothly into the second round with a clinical display of control and consistency. Djoković's dominant opening victory suggests he remains well-positioned for another deep run at the French Open.