Nicolas Jarry defeated Stéfanos Tsitsipás 3–6, 7–5, 6–4 in the Rome Masters quarter-final on clay on 16 May 2024, securing a significant upset victory against the pre-match favourite. Tsitsipás, seeded higher and backed by odds of 1.27 to Jarry's 4.2, dominated the opening set but failed to maintain his level thereafter. Jarry's comeback through the second set proved decisive, as the Chilean weathered Tsitsipás's initial pressure and gradually asserted control on the red clay. The Chilean's ability to recover from a set down and convert opportunities in the closing stages demonstrated improved clay-court form. This result marks a notable scalp for Jarry and raises questions about Tsitsipás's consistency on the surface heading into the French Open.