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The Boston Red Sox defeated the Detroit Tigers 10–3 on May 5 at Comerica Park, with the visitors' offensive output overwhelming Detroit's pitching staff. Boston's three home runs and ten RBIs powered the decisive victory, while the Red Sox held the Tigers to just seven hits and three runs despite allowing twelve strikeouts from Detroit's pitchers. The Tigers managed only a .725 OPS and struck out twelve times at the plate, unable to capitalize on limited opportunities against Boston's pitching, which surrendered just seven hits with a 4.11 ERA. Boston's 12 hits and balanced offensive approach—supplemented by their power display—proved sufficient to overcome their own 11 strikeouts and moderate .679 OPS. Detroit's defensive miscue and inability to generate consistent contact highlighted their struggles in the matchup. The Red Sox's seven-run margin suggests they may be finding rhythm offensively heading into their next divisional tests.