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The Boston Red Sox defeated the Pittsburgh Pirates 6–3 on March 22 at LECOM Park in a spring training matchup that saw the visitors capitalize on superior contact and pitching efficiency. Boston's offense generated 10 hits and 5 RBIs while striking out 11 times, posting a .737 OPS compared to Pittsburgh's .736, a nearly identical offensive profile that masked the Red Sox's ability to convert opportunities into runs. The Pirates' pitching staff allowed 10 hits and 6 earned runs with a 4.54 ERA, while committing 2 defensive errors that contributed to Boston's advantage. Boston's pitchers limited Pittsburgh to just 5 hits and 3 earned runs despite a 5.59 ERA, striking out 10 batters and walking only 2. Pittsburgh's 2 home runs and 10 strikeouts underscored a free-swinging approach that failed to generate consistent run production, with the team managing only 3 runs on 5 hits. The result suggests Boston's pitching depth may provide early-spring stability despite elevated ERA figures, while Pittsburgh's offensive inconsistency and defensive lapses could signal adjustment needs heading into the regular season.