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The Cleveland Guardians defeated the Cincinnati Reds 7–4 on May 16 at Progressive Field in a matchup that saw both offenses struggle against the Vegas total of 1. Cleveland's pitching staff struck out 8 batters while allowing just 5 hits and 4 earned runs, posting a 3.88 ERA despite yielding 7 walks. The Guardians' lineup managed only 10 hits with a .692 OPS but capitalized on their opportunities, driving in 5 runs and committing no errors in the field. Cincinnati's offense was even more anemic, mustering just 5 hits and a .701 OPS while striking out 8 times; the Reds' pitching was less efficient, surrendering 10 hits and 6 earned runs with a 4.68 ERA. The home team's defensive discipline proved decisive in a low-scoring affair where neither team's bats came alive. Cleveland's pitching advantage and Cincinnati's pitching vulnerability could shape the teams' run differential and playoff positioning as the season progresses.