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The St. Louis Cardinals edged the San Diego Padres 3–2 on June 16 at Busch Stadium in a low-scoring affair that fell short of the 8.5-run Vegas total. The Cardinals' pitching staff dominated, striking out eight batters while allowing just four hits and two earned runs with a 4.06 ERA, though the offense sputtered with only eight hits and a .721 OPS. San Diego's lineup was even more anemic, managing just four hits and an .647 OPS while striking out eight times; the Padres' pitching proved more efficient with a 3.89 ERA but surrendered eight hits and three earned runs. The Cardinals' five walks and clean defensive effort proved decisive in a game where both teams struggled offensively—a trend that suggests run-starved performances may persist as St. Louis continues its rotation through this series.