Marco Cecchinato defeated Alexander Bublik 7–6, 1–0 (retired) in the first round of the ATP 250 Winston Salem event on hard court on 19 August 2019. Bublik, the pre-match favourite at 1.61 odds, was unable to maintain his advantage after losing a competitive opening set in a tiebreak; Cecchinato, available at 2.46, capitalised on the momentum and broke serve early in the second set before Bublik's retirement handed the Italian an upset victory. The result marked a significant turnaround for Cecchinato, who recovered from a first-set deficit to progress to the second round.