Jannik Sinner defeated Alexei Popyrin 6–3, 6–2, 6–2 in the first round of the US Open on hard court, confirming his status as the overwhelming pre-match favourite at odds of 1.02. Popyrin, a 14.88 outsider, offered minimal resistance across the three sets, with Sinner controlling proceedings from the outset to secure a dominant victory. The Italian's clinical performance underscored his credentials as a leading contender for the title, whilst Popyrin's exit marked an early departure for the Australian. Sinner's progression sets up a second-round clash against a qualifier or lower-ranked opponent, maintaining his trajectory towards the latter stages of the tournament.