Despina Papamichail defeated Lin Zhu 1–6, 7–6, 6–0 in the first round of the WTA 250 event in Monastir on hard court on 3 October 2022, overturning pre-match expectations as the underdog. Zhu, the clear favourite at 1.22 odds, controlled the opening set decisively, but Papamichail rallied to force a second-set tiebreak, which she won to level the match. The Greek player then dominated the decider, dropping just six points to secure a comprehensive victory. The comeback result represents a significant upset and suggests Papamichail has the resilience to trouble higher-ranked opponents in this tournament.