Tereza Valentova defeated Lucia Bronzetti 6-3, 3-6, 6-4 in the first round of the US Open on hard court on 24 August 2025, confirming her status as the clear pre-match favourite. Bronzetti, the significant underdog at 4.33 odds, competed competitively through the middle set but could not sustain the momentum into the decider. Valentova's victory in the opening round positions her to face the next challenge in the draw.