Iva Jovic defeated Aliaksandra Sasnovich 7–6, 6–3 in the first round of the US Open on hard court on 25 August 2025, confirming her status as the clear pre-match favourite. Despite Sasnovich's resistance in a competitive opening set that went to a tie-break, Jovic controlled the second frame to secure a straightforward passage into the second round. The result reflects the odds positioning, with Jovic's odds of 1.28 validating her stronger seeding and form heading into the tournament. This victory keeps Jovic on course in the draw and establishes early momentum on the hard courts at Flushing Meadows.