Amanda Anisimova defeated Magdalena Frech 6–2, 4–6, 6–3 in the round of 16 at the WTA 250 event in Berlin on grass on 19 June 2025. Anisimova, the pre-match favourite at odds of 1.29, secured the victory as expected, though Frech mounted a competitive middle set at 3.95 odds before the American reasserted control in the decider. The result maintains Anisimova's progression through the Berlin draw as she advances to the quarter-finals.