Reilly Opelka defeated Giovanni Mpetshi Perricard 6–3, 7–6 in the Brisbane ATP 250 semi-final on hard court on 4 January 2025, an upset victory over the pre-match favourite. Opelka, priced at 2.30 to Perricard's 1.69, converted his opportunity to reach the final with a composed performance that saw him secure the opening set convincingly before edging a competitive second-set tie-break. The result marks a significant scalp for the American and suggests strong form heading into the tournament's final round.