Chicago Fire's US Open Cup campaign ended in disappointment with a 2–1 defeat to St. Louis City on 30 April. The hosts dominated territorially, registering 12 shots, but their profligacy proved costly; only one effort found the target as they struggled to break down City's 3–4–2–1 shape. St. Louis, operating with greater efficiency, converted their limited opportunities into a decisive victory, with Eduard Lowen and Tomas Totland securing the goals. The visitors' five shots on target underscored a clinical finishing display that contrasted sharply with Chicago's wastefulness in front of goal. Chicago's goalkeeper conceded 1.0 post-shot expected goals, indicating the quality of City's finishing, while the Fire's 4–3–3 setup failed to generate clear-cut chances despite controlling play. This result marks a significant setback for Chicago's cup ambitions in what proved a frustrating night of missed chances.