Alexander Zverev defeated Thanasi Kokkinakis 6–3, 6–4 in the quarterfinals of the ATP 250 Los Cabos event on hard court, confirming his status as the clear pre-match favourite with odds of 1.17 to Kokkinakis's 5.88. The German top seed controlled proceedings throughout, breaking serve twice in each set to advance smoothly into the semi-finals. Kokkinakis, competing as the underdog, offered limited resistance on the Californian hard courts, unable to generate the pressure required to trouble Zverev's serve or dictate rallies from the baseline. The victory maintains Zverev's momentum in the early season and sets up a favourable path towards the title.