Amanda Anisimova defeated Naomi Osaka 6-7 7-6 6-3 in the US Open semi-final on hard court on 4 September 2025, an upset victory against the pre-match favourite. The American saved a set point in the opening tiebreak before claiming the second set in another tiebreak, then dominated the decider to reach the final. Anisimova's comeback performance from a set down against the slight favourite represents a significant scalp at the year's final Grand Slam and sends her into the championship match as a player in commanding form.