Antonia Ruzic defeated Tyra Caterina Grant 3–6, 6–3, 7–5 in the first round of the Rome Masters on clay. As the pre-match favourite at odds of 1.59, Ruzic's victory followed expectations, though Grant mounted a competitive challenge after losing the opening set. The American forced a decider by levelling the match in the second set, but Ruzic's superior ranking and experience proved decisive in a tight third frame. The result confirms Ruzic's status as a dangerous clay-court competitor at the elite level and sets up a second-round encounter at one of the year's most prestigious tournaments.