Nuria Parrizas Diaz defeated Arantxa Rus 7–6, 2–6, 6–1 in the round of 16 at the WTA 250 event in Bogota on clay on 7 April 2021, an upset over the pre-match favourite Rus, who carried odds of 1.49 to Parrizas Diaz's 2.82. The Spaniard secured a tight opening set via tiebreak before losing the second set decisively, then dominated the third to secure a commanding victory. The result marked a significant upset and demonstrated Parrizas Diaz's ability to recover from adversity on clay, where her countrywoman Rus was expected to prevail.