Camilo Ugo Carabelli upset favoured Aslan Karatsev 6–3, 4–6, 6–4, 3–6, 7–6 in the first round of Roland Garros on clay on 22 May 2022. The Argentine qualifier, priced at 2.43 against Karatsev's 1.63 odds, recovered from losing the opening set and surrendering the third to force a deciding fifth set, where he ultimately prevailed in a tight tiebreak. The five-set marathon showcased Carabelli's resilience against the higher-ranked Russian, who had entered as the tournament favourite. The victory marked a significant scalp for Carabelli in his Roland Garros campaign and demonstrated his capacity to compete at the highest level on clay.