Naomi Osaka defeated Sara Errani 6–2, 6–3 in the first round of the Rome Masters on clay on 7 May 2025, comfortably dispatching the Italian as the heavy pre-match favourite. Osaka's odds of 1.09 reflected her status as overwhelming favourite against Errani's 9.0, and the Japanese former world number one validated that assessment with a straightforward performance that saw her control both sets. The result extends Osaka's positive momentum on the clay-court circuit ahead of the tournament's later rounds.