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The San Francisco Giants defeated the Baltimore Orioles 6–3 on April 10 at Oriole Park at Camden Yards, with the visitors' offense outpacing a low-scoring contest that fell well short of Vegas's over-under projection. San Francisco's 12 hits and two home runs generated six runs and six RBIs, while their pitching staff held Baltimore to eight hits and three earned runs with a 3.96 ERA. The Orioles managed just eight hits and one home run despite drawing four walks, posting a weak .696 OPS that underscored offensive struggles early in the season. Both teams struck out six times, but the Giants' two-homer advantage proved decisive in a game where Baltimore's pitching allowed six earned runs across a 4.09 ERA outing. The Giants' superior run production on comparable contact rates suggests their lineup depth and power potential may sustain them through April, while Baltimore's offensive inconsistency—evidenced by a .241 batting average—will need correction as the season progresses.