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The Baltimore Orioles defeated the San Francisco Giants 6–2 on April 12 at Oriole Park at Camden Yards, with the home team's balanced offensive attack overwhelming a listless Giants lineup. Baltimore's pitching staff struck out seven while allowing just seven hits and no walks, posting a 3.74 ERA in the victory. The Orioles generated 11 hits and drove in all six runs on a single home run, while San Francisco managed only seven hits and two RBIs despite matching Baltimore's strikeout total. The Giants' pitching proved vulnerable, surrendering 11 hits and six earned runs while issuing five walks—a sharp contrast to Baltimore's clean execution. San Francisco's .645 OPS and inability to generate offensive pressure underscored their struggles, as the team failed to capitalize on opportunities despite the modest Vegas total of 1. The Orioles' error-free defense and disciplined approach at the plate will be critical factors as both teams navigate early April, particularly for San Francisco's need to tighten its pitching control in upcoming matchups.