Liudmila Samsonova defeated Aliaksandra Sasnovich 6–1, 6–3 in the final of the WTA 250 Cleveland event on hard court on 27 August 2022, confirming her status as pre-match favourite. Samsonova's dominant performance saw her claim the title with a comprehensive victory, dropping only four games across two sets. The result extended Samsonova's momentum in 2022 and marked a significant trophy for the Russian player at a 250-level event. This victory underscores Samsonova's growing consistency on hard courts and her ability to perform under pressure in finals.