Anastasia Pavlyuchenkova defeated Taylah Preston 6–2, 6–0 in the first round of the US Open on hard court on 27 August 2024, confirming her status as the heavy pre-match favourite with odds of 1.11. The Russian produced a dominant display, conceding just two games across two sets against the Australian qualifier, who entered at 7.97 odds. Pavlyuchenkova's commanding performance—dropping only a single break of serve in the opening set before shutting out her opponent entirely in the second—demonstrated the gulf in class between the two players. The result sends the seeded Russian through to the second round with considerable momentum.