Fiona Ferro defeated Angelina Gabueva 6–3, 6–4 in the first round of the WTA 250 event in Strasbourg on clay on 17 May 2022. Ferro, the overwhelming pre-match favourite at odds of 1.05, secured a straightforward victory as expected, dropping only seven games across two sets. Gabueva, a significant underdog at 12.56, offered limited resistance on the surface. The result was a routine progression for Ferro, who controlled the match with minimal fuss to advance to the second round.