Carlos Alcaraz defeated Hamad Medjedovic 6–4, 6–4 in the second round of the Cincinnati Masters on hard court, confirming his status as the heavy pre-match favourite with odds of 1.18 to Medjedovic's 5.63. The Spanish top seed controlled proceedings throughout, securing two consecutive breaks of serve in each set to advance efficiently without facing significant resistance. Alcaraz's composed performance maintained his momentum in Cincinnati, where he continues to pursue silverware at one of the ATP's premier Masters 1000 events. The result keeps him on track for a deep run at the tournament.