Dominic Thiem defeated J J Wolf 6–7 7–5 7–6 in the first round of the ATP 250 event at Winston Salem on hard court on 22 August 2022. Thiem, the pre-match favourite at 1.84 odds, secured victory in a competitive three-set encounter that went to tiebreaks in both the opening and final sets. Wolf, at 2.06 odds, mounted a strong challenge but ultimately fell short in the decisive moments. The Austrian's ability to recover from the opening-set loss and edge through the second set proved decisive in a match that required resilience and composure. The result marks a solid early-tournament performance for Thiem as he looks to build momentum in the latter stages of the North American hardcourt swing.