Nick Kyrgios defeated J J Wolf 6–4, 6–2, 6–3 in the second round of the 2022 US Open on hard court, confirming his status as pre-match favourite with odds of 1.16 against Wolf's 6.13. The Australian's commanding performance saw him progress smoothly through the early stages of the tournament, dropping only four games in the second and third sets. Kyrgios's clinical display underlined his ability to impose his game on hard courts, where his serve and aggressive play typically prove most effective. The result represented a straightforward victory for the higher-ranked player and suggested Kyrgios was building momentum as the fortnight progressed.