Jessica Bouzas Maneiro defeated Mayar Sherif 6–3, 6–1 in the first round of the Madrid Masters 1000 on clay on 22 April 2025, securing an upset victory against the pre-match favourite. Despite Sherif entering as the betting favourite at 1.80 odds to Bouzas Maneiro's 2.11, the Spanish player dominated the encounter with a commanding performance across both sets. The decisive margin—winning the opening set by three games and the second by five—underscored Bouzas Maneiro's control throughout the match. The result represents a significant statement for Bouzas Maneiro on the Madrid clay, one of the tour's premier surfaces, and marks a confidence-building victory as she progresses deeper into the tournament.