Novak Djoković defeated Juan Pablo Varillas 6–3, 6–2, 6–2 in the fourth round of Roland Garros on clay on 4 June 2023, a result that aligned entirely with pre-match odds, with Djoković heavily favoured at 1.04 to Varillas's 18.34. The Serbian top seed dismantled the Peruvian qualifier with clinical efficiency, dropping only seven games across three sets to advance smoothly to the quarter-finals. Varillas, competing in the main draw at Roland Garros for the first time, offered little resistance against the world's dominant clay-court player. The comprehensive nature of the victory underscored Djoković's imperious form on the Paris surface and his continuing pursuit of a record-extending fourth French Open title.