Karolína Muchová defeated Marta Kostyuk 6-3, 6-7, 6-3 in the US Open Round of 16 on hard court, confirming her status as the pre-match favourite with odds of 1.68 to Kostyuk's 2.32. Muchová dominated the opening set with a commanding 6-3 victory, though Kostyuk mounted a competitive response in the second, forcing a tie-break which the Ukrainian narrowly won to level the match. The Czech player reasserted control in the decider, securing another 6-3 scoreline to advance to the quarter-finals. The result underscores Muchová's solid form on the hard courts of New York, whilst Kostyuk's inability to convert the momentum from the second-set tie-break proved costly in her bid to progress further.