Qinwen Zheng defeated Ons Jabeur 6-2, 6-4 in the US Open Round of 16 on hard court on 4 September 2023, delivering a significant upset against the pre-match favourite. Jabeur entered as the betting favourite at 1.64 odds, with Zheng at 2.42, yet the Chinese player dominated the encounter with a composed performance across both sets. The decisive scoreline underscored Zheng's superiority throughout the match, as she broke down Jabeur's typically aggressive game with consistent play and efficient court coverage. The result marked a notable progression for Zheng in a Grand Slam environment and represented a setback for Jabeur's campaign at Flushing Meadows, where consistency had eluded her across multiple surfaces this season.